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4-Hydroxynonenal 4-Hydroxynonenal (4HNE) is a lipoperoxidation-derived aldehyde that can damage proteins and DNA through the generation of covalent adducts and is implicated in the control of cell signaling 13,14

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Despite advances in the understanding of disease pathogenesis, and the increased availability of treatment options, the prevalence of ESRD continues to rise in people living with T2DM [6]

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